Contributions to the free energy of binding for the formation of an enzyme-substrate complex can come from the following interactions between the enzyme and substrate:

Your internet settings won't let you play MightyQuiz. :(

But... we've got a solution!

• 1) Turn on cookies in your browser.
• 2) Reload the page.
• 3) Play! :)

Your internet settings won't let you play on Everyday Scientist. :(

But... we've got a solution! :)

You can play in a new window here. Easy!